Case Study

Columbia Medical Center


Columbia Medical Center wanted to understand how different light therapy interventions affect mood in cancer survivors. They wanted to perform a mobile-based clinical trial using an n-of-1 study methodology.


Columbia’s patients received a customized iOS app to track their steps, mood, medication symptoms and light therapy adherence for three months. The three months were split into four arms using an ABBA schedule. Researchers received a customized dashboard showing how the measurements changed during intervention arms A and B.


Results will be forthcoming.

Patients have found Overlap easy to use and compliance has been excellent! Thanks to Overlap, we have been able to demonstrate the feasibility of Personalized Trials in the mobile health era.

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